- 教室【きょうしつ】 - classroom, lecture room, department (in a university), class, lessons, course, school (for a particular discipline), teaching establishment 
- 寝室【しんしつ】 - bedroom 
- 室長【しつちょう】 - section chief, laboratory manager, office head, room monitor 
- 王室【おうしつ】 - royal family 
- 地下室【ちかしつ】 - cellar, basement 
- 氷室【こおりむろ】 - ice house, ice room, cold room 
- 病室【びょうしつ】 - sickroom, hospital room, ward 
- 浴室【よくしつ】 - bathroom 
- 室内【しつない】 - indoor, inside the room 
- 温室【おんしつ】 - greenhouse, hothouse, conservatory, glasshouse 
- 客室【きゃくしつ】 - guest room (at a hotel), guest cabin (on a boat), passenger cabin (on a plane), drawing room 
- 事務室【じむしつ】 - office (room) 
- 和室【わしつ】 - Japanese-style room 
- 更衣室【こういしつ】 - locker room, changing room, dressing room 
- 入室【にゅうしつ】 - entering a room, studying under a Buddhist teacher 
- 洋室【ようしつ】 - Western-style room 
- 茶室【ちゃしつ】 - tearoom, tea house, tea-ceremony room, tea arbour, tea arbor 
- 皇室【こうしつ】 - Imperial household 
- 会議室【かいぎしつ】 - conference room, council room 
- 研究室【けんきゅうしつ】 - laboratory, seminar room, professor's office