失業【しつぎょう】
unemployment, losing one's job, becoming unemployed
損失【そんしつ】
loss (of assets, profit, etc.)
失敗【しっぱい】
failure, mistake, blunder
失う【うしなう】
to lose, to miss (a chance, opportunity), to lose (a loved one), to be bereaved of, to concede (goals, points, etc.)
過失【かしつ】
accident (caused by negligence), error, blunder, fault, defect
失望【しつぼう】
disappointment, despair
喪失【そうしつ】
loss, forfeit
失格【しっかく】
disqualification, elimination, incapacity, being unfit for one's role, being a failure
失脚【しっきゃく】
losing one's position, losing one's standing, downfall, fall (from power), being overthrown
失意【しつい】
disappointment, despair, despondency, broken heart, adversity
紛失【ふんしつ】
loss, going missing
失墜【しっつい】
abasement, fall, forfeiture, sinking (in people's estimation)
失神【しっしん】
faint, swoon, losing consciousness
失礼【しつれい】
discourtesy, impoliteness, excuse me, goodbye, to leave, to be rude
失恋【しつれん】
disappointed love, broken heart, unrequited love, being lovelorn
失敬【しっけい】
rudeness, impoliteness, disrespect, impertinence, leaving, going (on one's way), saying goodbye, taking without permission, stealing, pinching, pilfering, my apologies, I must be going now, so long
見失う【みうしなう】
to lose sight of, to miss